Differential Leaflet Remodeling of Bone Marrow Cell Pre-Seeded Versus Nonseeded Bioresorbable Transcatheter Pulmonary Valve Replacements
نویسندگان
چکیده
منابع مشابه
Mitral Valve Leaflet Remodeling After Myocardial Infarction
It is a matter of force. It is a balance of valve closing force and tethering force that affects mitral valve coaptation. Ischemic mitral regurgitation develops secondary to left ventricular dysfunction generally with structurally normal leaflets. However, it seems it is not simply a matter of force when we see the fact that valve leaflets histologically change after myocardial infarction. The ...
متن کاملTranscatheter Pulmonary Valve Replacement
Transcatheter pulmonary valve replacement (tPVR) has evolved into a viable alternative to surgical conduit or bioprosthetic valve replacement. This procedure has paved the way for a more advanced approach to congenital and structural interventional cardiology. Although many successes have been noted, there are still a number of challenges with this procedure, including large delivery systems, t...
متن کاملPreliminary experience using the transcatheter mitral valve leaflet repair procedure.
BACKGROUND Mitral regurgitation (MR) causes increased morbidity and mortality in heart failure patients and is often associated with augmented surgical risk. OBJECTIVES To assess the preliminary results oftranscatheter mitral valve leaflet repair (TMLR) in a single academic center. METHODS Data were collected prospectively in the cardiology department of Rabin Medical Center in 2012. Ten co...
متن کاملEctopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft.
Improvements to current therapeutic strategies are needed for the treatment of skeletal defects. Bone tissue engineering offers potential advantages to these strategies. In this study, ectopic bone formation in a range of scaffolds was assessed. Vital autograft and devitalised allograft served as controls and the experimental groups comprised autologous bone marrow derived stem cell seeded allo...
متن کاملTranscatheter pulmonary valve implantation in native pulmonary outflow tract using the Edwards SAPIEN™ transcatheter heart valve.
Percutaneous pulmonary valve implantation (PPVI) is now an accepted alternative option to conventional surgery for patients with dysfunctional conduits between the right ventricle and pulmonary artery. PPVI will reduce the total number of repeat operations in such patients. However, surgery remains the primary option in postoperative tetralogy of Fallot patients with severe pulmonary regurgitat...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2020
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2019.09.008